COMPUTER-AIDED ANALYSIS OF QUERCETIN MECHANISM OF OVERCOMING DOCETAXEL RESISTANCE IN DOCETAXEL-RESISTANT PROSTATE CANCER

Computer-aided analysis of quercetin mechanism of overcoming docetaxel resistance in docetaxel-resistant prostate cancer

Abstract Background Prostate cancer (PC) is a silent but potent killer among men.In 2018, PC accounted for more than 350, 000 death cases while more than 1.2 million cases were diagnosed.Docetaxel, a chemotherapeutic drug belonging to the taxane family of drugs, is one of the most potent drugs in combating advanced PC.However, PC cells often evolve

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Extremely elevated IL-18 levels may help distinguish systemic-onset juvenile idiopathic arthritis from other febrile diseases

The aim of this research was to explore whether IL-18 can be a serological marker for the diagnosis of systemic-onset juvenile idiopathic arthritis (sJIA).A total of 23 sJIA patients (13 males, median age Lifeguard Hat 8.2), 20 acute lymphoblastic leukemia (ALL) patients, 18 patients with severe infections (SIF), 26 Kawasaki disease (KD) patients,

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GP-9s are ubiquitous proteins unlikely involved in olfactory mediation of social organization in the red imported fire ant, Solenopsis invicta.

The red imported DVI fire ant (RIFA), Solenopsis invicta, is an invasive species, accidentally introduced in the United States that can cause painful (sometimes life-threatening) stings to human, pets, and livestock.Their colonies have two social forms: monogyne and polygyne that have a single and multiple functional queens, respectively.A major ge

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